Fractional exhaled nitric oxide (FeNO) is a noninvasive marker of eosinophilic airway inflammation. FeNO measurement is easily done and results are immediately available.
FeNO measurement is gradually becoming part of the routine evaluation of patients with asthma for both diagnosis and guide in asthma control. FeNO level is normal in well-controlled asthma.
Active and passive smoking decreased FeNO levels in adults.
nNOIn patients with sinusitis, nasal nitric oxide (nNO) is decreased, and it rises up after a course of antibiotics.
nNO is also low in primary ciliary dyskinesia and can probably be used as a screening test.
Hand-held FeNO deviceThe current chemiluminescence FeNO analyzers (e.g.
NIOX) are costly and lack transportability. Newer hand-held devices are available (
NIOX MINO), and according to a
recent study, they are just as reliable as their bulkier counterparts. The price of one NIOX MINO unit is around $ 4,200.
Exhaled nitric oxide correlated with control in recurrent infantile wheeze treated with inhaled corticosteroids.
http://goo.gl/AS7I