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Beranda » allergy » Contact Dermatitis » contact dermatitis society » cosmetic allergy » itchy skin » methyisothiazolone » patch testing » personal care product allergy » preservative » rash » skin rash » toilet wipes » Roll out the Red Carpet....the winner is!

Roll out the Red Carpet....the winner is!

Each year the American Contact Dermatitis Society chooses an allergen of the year.  There's not as much pomp and circumstance as the Oscars but it's a big win.  This  award draws attention to allergens that are very common and/or under recognized.  Chemicals are chosen based on their prevalence in products and relevance of causing allergic reaction. 


The 2013 winner is..... 

Methylisothiazolinone


What is methylisothiazolone (MI)?
  • MI was first introduced  in cosmetics, toiletry and suncreen products in 2005.
  • It's used as a preservative to kill bacteria and fungus.
  • In the 1980's, it was used in combination in high doses (15 ppm) with a preservative called methylcholoroisothiazolinine/methylisothiazolone in (MC/MI) "leave in" products like shampoo and conditioner
  • After the MC/MI introduction about 8% of people had reactions to the recommended doses, and concentrations were reduced to 7.5 PPM in the late 80's and early 90's
  • In 2000, MI was pulled out of the MC/MI combination with the hopes that it wouldn't be as strong of a cause of allergic reaction.  They thought it was a weaker sensitizer
  • Even though they pulled it out, they didn't limit concentrations!  And concentrations increased by 25 X
  • In 2004-5, the first case reports of MI allergy were described after wallpapering and using paint.
  • Only 7 years ago, we started seeing reports of people developing allergic reactions in wet toilet paper
  • Since 2007, the use of MI as a preservative has doubled along with reactions
  • We currently don't know how common MI allergy is.
Where do you find  methylisothiazolone (MI)? - Almost any product that you'd put on your body.
  • Cosmetics
  • Baby products (lotions, oils, creams, and powder)
  • Makeup
  • Body Washes
  • Hair care products (shampoo, conditioner, straighteners, rinses
  • Hair coloring products 
  • Nail care products
  • Deodorants
  • shaving products
  • Skin care products
  • Sunscreen
  • Wet Wipes (babies, and moist towelettes)
When should you suspect you have a methylisothiazolone (MI) allergy?
  • MI allergy is common but difficult to distinguish from other preservatives that are use in many personal care products.
  • Consult an allergist/immunologist (Find an Allergist) or dermatologist if you have an itchy rash that won't go away.
  • They'll perform patch testing and then you'll know!


Want more information?
  • http://www.contactderm.org/i4a/pages/index.cfm?pageid=1
  • http://www.allergeaze.com/PDFs/AP/AP123-124.pdf
  • http://en.wikipedia.org/wiki/Methylisothiazolinone
  • Info on Contact dermatitis
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